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Search results for Paolo U. Giacomoni

Diabetic Skin: targeted soothing and support

Published on Issues - Year 2018
Authors Vincenzo P.M. Rialdi , Paolo U. Giacomoni  

Introduction In 2014, the prevalence of diabetes-linked pathologies was estimated to be of the order of 420 million worldwide, up from 108 million in 1980 (1). That is to say that one person out of sixteen is suffering from a diabetic pathology. In particular, the prevalence of diabetes in adu...

Tags extracellular matrix, Filagrinol, soothing, diabetes, skin aging, advanced glycation endproducts, glucose, Collagenon, mmp, lang_en, Trioxene-LV, matrix metallo proteinases, Folliculitis, Erythrasma, collagen, Haemochromatosis, moisturization, micro-angiopathy, Hyperpigmented atrophic lesions, Necrobiosis lipoidica diabeticorum, skin resiliency, elasticity, Xanthoma, Perforating dermatosis, Persistent erythema, Acanthosis nigricans, Salycuminol, anti-inflammatory, Diabetic ulcers, elastic fibers, Diabetic dermopathy, dermis, Dermonectin, glycation, Aminoefaderma, fibronectin, Extensive Granuloma Annulare, AGEs, Diabetic skin, Porphyria Cutanea Tarda, Scleredema diabeticorum, curcumin, Hyaluramine-S, Carotenodermia, ACS-AntiCytoStressor, Diabetic bullae, keratinization


Cute diabetica supporto ed interventi mirati

Published on Issues - Year 2018
Authors Vincenzo P.M. Rialdi , Paolo U. Giacomoni;  

INTRODUZIONE La patologia diabetica nelle sue varianti affligge oltre quattrocentoventi milioni (2014) di soggetti nel mondo, contro i centootto milioni del 1980(1). Vale a dire che una persona su sedici soffre di una patologia diabetica. In particolare l'incremento fra gli adulti di oltre diciotto...

Tags extracellular matrix, Filagrinol, soothing, diabetes, skin aging, advanced glycation endproducts, glucose, lang_it, Collagenon, mmp, lang_en, Trioxene-LV, matrix metallo proteinases, Folliculitis, Erythrasma, collagen, Haemochromatosis, moisturization, micro-angiopathy, Hyperpigmented atrophic lesions, Necrobiosis lipoidica diabeticorum, skin resiliency, elasticity, Xanthoma, Perforating dermatosis, Persistent erythema, Acanthosis nigricans, Salycuminol, anti-inflammatory, Diabetic ulcers, elastic fibers, Diabetic dermopathy, dermis, Dermonectin, glycation, Aminoefaderma, fibronectin, Extensive Granuloma Annulare, AGEs, Diabetic skin, Porphyria Cutanea Tarda, Scleredema diabeticorum, curcumin, Hyaluramine-S, Carotenodermia, ACS-AntiCytoStressor, Diabetic bullae, keratinization


Activities of Excipients for Topical Skin Care Formulations

Published on Issues - Year 2017
Author Paolo U. Giacomoni  

INTRODUCTION Far from being inactive bystanders of the pharmacological activity, excipients can play relevant roles in skin care products. Aesthetically pleasing emulsions owe their light touch or sensual feeling to carefully selected excipients able to improve spreadability without diminishing vis...

Tags rheological, acetylated Glycol Stearate, lang_en, emulsifier, dispersion, Xalifin-15, stability, eudermic, oil, wax, absorption, peroxides, saturated, C12-20 Acid PEG-8 Ester, comedogenic, Cetacene, coefficient octanol / water, penetration, C10-18 Triglycerides, sensory, Nesatol, Excipients, plasticity, sebum-like, vehiculation safety, bioemulgoid


Eccipienti attivi per formulazioni topiche

Published on Issues - Year 2017
Author Paolo U. Giacomoni  

INTRODUZIONE Lungi dall’essere esclusivamente inerti testimoni dell’azione farmacologica, gli eccipienti possono avere una funzione molto importante nei prodotti di applicazione topica per la cura della pelle. Le qualità estetiche dei prodotti sono dovute alla scelta oculata di eccipienti capaci di...

Tags stabilità, lang_it, cera, Xalifin-15, saturo, comedogenico, C10-18 Trigliceridi, C12-20 Acid PEG-8 ester, reologico, sensoriale, dispersione, Eccipiente, Cetacene, assorbimento, Nesatol, emulsionante, perossidi, plasticità, bioemulgoide, Acetylated Glycol Stearate, sebosimile, penetrazione, coefficiente ottanolo/acqua, veicolazione olio, eudermico


Auxina - Effects on human hair and beard growth by topical application of a calibrated blend of botanical extracts (*)

Published on Issues - Year 2016
Author Paolo U. Giacomoni  

A remarkable segment of the personal care market is represented by personal care products for men. It has been estimated that this market (~4 bn $ in the USA alone in 2013 and perhaps six-seven times larger, worldwide) is comparable, in size, to the budget of the National Insitutes of Health...

Tags normalization, scalp, exogen, lang_en, kenogen, trichogram, follicle, flavonoids, adenylate cyclase, stimulation, re-growth, hairs, estrone, auxina tricogena, beard, alopecia, telogen, azelaic acid, growth, hair, anagen, catagen, 5-alpha-reductase


Auxina - Effetto di una miscela calibrata di estratti botanici (*) sulla crescita di capelli e barba

Published on Issues - Year 2016
Author Paolo U. Giacomoni  

I prodotti di cura per uomo rappresentano una notevole frazione del mercato dei prodotti per la cura personale, infatti questo mercato è stimato in 4 miliardi di dollari per i soli Stati Uniti, globalmente è valutato sei-sette volte tanto ed è quindi paragonabile al fatturato dei NIH...

Tags flavonoidi, peli, lang_it, stimolazione, exogen, kenogen, adenilato ciclasi, normalizzazione, capello, ricrescita, 5-alfa reduttasi, estrone, cuoio capelluto, tricogramma, auxina tricogena, alopecia, telogen, barba, anagen, catagen, acido azelaico, crescita, follicolo


Human Stratum Corneum homeostasis: the relevance of filaggrin and of inducers of filaggrin production

Published on Issues - Year 2016
Author Paolo U. Giacomoni  

A remarkable aspect of epidermal physiology is the repair strategy of the stratum corneum: instead of carrying out punctual removal of damage, the stratum corneum undergoes a permanent renewal. In the basal layer individual cells remove DNA damage and "chaperone" damaged proteins to the lysosomes th...

Tags loricrin, Filagrinol, proline, profilaggrin, Factor, UV, keratin, envelope, corneocytes, lang_en, corneum, skin, psoriasis, hydration, Stratum, NMF, ichthyosis, Urocanic, epidermis, histidine, Filaggrin, granulosum, Moisturizing, keratinization, Natural


Omeostasi dello strato corneo umano: importanza della filaggrina e degli induttori della produzione della filaggrina

Published on Issues - Year 2016
Author Paolo U. Giacomoni  

Un aspetto notevole della fisiologia dell’epidermide si riscontra nell’analisi della strategia di riparazione nello strato corneo: anziché rimuovere i singoli danni, lo strato corneo è sottoposto ad un continuo processo di rinnovamento. Mentre nello strato basale i cheratinociti riparano il DNA e gu...

Tags Filagrinol, Corneociti, UV, Involucro, Epidermide, Idratazione, Loricrina, lang_en, Stratum corneum granulosum, Filaggrina, Psoriasi, NMF, Pelle, Cheratina, Cheratinizzazione, Ittiosi, Istidina, Profilaggrina, Prolina, Urocanico, Natural Moisturizing Factor