APPLICATION OF HPTLC IN THE PRELIMINARY RESEARCH OF PESTICIDES AND PCBs IN COSMETIC PRODUCTS
Authors Cristina Neuhoff , Carla Villa , Stefano Dorato
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Tags biphenyls, polychlorinated, cosmetic, lang_en, layer, cromatography, products, thin, high, botanicals, pesticides, performance, (HPTLC), lanolin, (PCBs)
Being resistant pollutants, polychlorinated biphenyls (PCBs), organochlorinated and organophosphate pesticides have already been detected in raw materials and finished cosmetics. This paper will introduce an HPTLC analytical procedure to detect PCBs, pesticides and their mixtures in cosmetics thus also allowing timesaving gas cromatographic determinations.
Organochlorine and organophosphate derivatives are widespread into the environment, occur in soil and water and are incorporated into various biological life cycles [1,2].
Poisoning of humans has been documented deriving from contamined food or occupational exposure. Hyperkeratosis, chloracne, irritant, allergic and phototoxic contact dermatitis have been reported following exposure to these chemicals [1,3,4].
Trace amounts of PCBs, organochlorinated and organophosphate pesticides might accidentally contaminate some raw materials, mainly botanicals, lanolin and its derivatives, and therefore might be present in consumer products.
Regulatory requirements and safety assessment for each cosmetic imply an accurate examination of impurities and unwanted contaminants which could be present in raw materials.
In previous papers we illustrated the gas cromatographic determination of PCBs, organochlorine and organophosphate pesticides in cosmetics containing plant oils and extracts, lanolin and its derivatives [5-7]. Before performing a gas cromatography with electron-capture detector, separation of pesticides and PCBs was necessary in order to avoid interference and superimposition of characteristic peaks [8-10].
Now we have developed an HPTLC method to perform a simple, rapid, reliable and accurate detection of PCBs and pesticides in cosmetic products and their ingredients.